In this study, we have structurally and functionally characterized the free standing ACBP's of Leishmania major. The function of these proteins in Leishmania is largely unknown. In Leishmania major, we have identified six Acyl-Co-A binding proteins. As the amastigote stage of Leishmania utilizes fatty acids as one of the source for energy production, these proteins might have importance in the parasite survival. ACBP gene has been reported to be essential in the blood stream form of Trypanosoma brucei, a close relative of Leishmania. ACBP's participate in acyl-Co-A transport, and functions in the intracellular acyl CoA pool formation. ACBP's have been reported to be involved in membrane biosynthesis, regulation of gene expression, and various enzyme activities related to the lipid metabolism.
Structure (x-ray/NMR/EM) ABS002 STRUCTURAL AND BIOPHYSICAL CHARACTERIZATION OF ACYL-CO-A BINDING PROTEINS OF LEISHMANIA MAJOR Shalini Verma 1 1National Institute of Immunology (New Delhi, India)Īcyl-Co-A-binding proteins (ACBPs) are small alpha helical proteins, ubiquitously present in all living systems. Aside from lecuring at Bath School of Art and Design, Camilla has taught at Sir John Cass Faculty of Art, Design and Architecture, Goldsmiths College, Kent Institute of Art and Design, and Holbaek Kunsthøjskolen in Denmark.13 – Metabolic Engineering/Energy ApplicationsĢ5 – Transcription/Translation/Post-Translational ModificationsĢ6 – Other 21. She has also curated exhibitions, amongst which were "Of and For" at the Bank, and "Mirei" in Unit 2, Whitechapel, with the artist Mary Maclean. Experience is collapsed into a moment, a moment is lived by an image, and the image extended through painting.Ĭamilla has been a Jerwood Contemporary Painters finalist and has shown her work solo in London at Fordham, Laurent Delaye, as well as in group shows at the Herbert Read gallery, Metropole Galleries, ArtSway, Salford, Dunkirk and Cardiff amongst others and outside the UK in Cologne, Vienna, Maribor and Berlin. Like a dream space, eliding boundaries of real and unreal, the work suggests that inhabiting an interior is more a psychological than a physiological state. As Peter Osborne refers to the fragment, "The independence of each individual fragment from others figures the idea of totality, from which the ensemble or collection of fragments derives both its necessity - as an externally imposed or constructed unity of a multiplicity, the unity of a montage - and its own sense of incompletion". The painted language here seeks to elaborate the incomplete as complete. Just as ruins do, they refer to a lost whole. These paintings are in a sense fragments. Sometimes, the places appear obsolete, unbound by function, defamiliarised, and so are free to take on new, chimerical qualities. Heightened colour emphasises a sense of spatial dislocation. Sometimes, the paintings work to delay recognition on the part of a viewer there is an uncertainty as to their reality. The sense that these interiors are not self-evident arises from the feeling that we might be looking at stage sets rather than actual interiors. "The 'Uncanny' is not a property of space itself, nor can it be provoked by any particular spatial conformation it is, in its aesthetic dimension a representation of a mental state of projection that precisely elides the boundaries of real and unreal in order to provoke a disturbing ambiguity, a slippage between waking and dreaming’. The emphasis is upon the sense of inhabiting inhabiting the space, and the image as a space. The paintings figure no human presence, but yet invoke its traces.
These are forms of ruin, places in transition between one state and the next, open to an ambiguity of reading and spatial experience. Recent painting embodies both the desire for an interior space and the negotiation of a representational language appropriate to this. She has configured the interior as a stage-like setting, the place of potential action, historical narrative, occupied by passed or multiple moments, and augmented, fractured, in reflection.
Search Search Bath Spa Go Camilla Wilson – Bath Spa UniversityĬamilla Wilson’s painting finds its focus in the space of the interior. Tackling harassment and sexual misconduct.Care leavers estranged students and carers.Student Route EU EEA and Swiss Nationals.Bath Spa University Pandemic Support Fund.